Michael Passarelli, PhD, MPH - COBRE-RIPS Seminar

"Bile acid signaling and microbial metabolism in colorectal cancer precursor lesions."

February 1, 2023
12 pm - 1 pm
Location
Dartmouth-Health Campus and Zoom
Sponsored by
Department of Epidemiology
Audience
Public
Registration required
More information
Lura Pascale

Michael Passarelli, PhD, MPH, will present COBRE-RIPS, "Bile acid signaling and microbial metabolism in colorectal cancer precursor lesions." Certain bile acids, including those generated by the gut microbiome, are toxic to colonocytes, but bile acid metabolism remains poorly characterized as a risk factor for developing colorectal adenomas and sessile serrated lesions. In this Research in Progress seminar, Dr. Passarelli will describe the aims and preliminary data for a grant application under development for a large integrative epidemiologic study that will reveal how bile acid metabolism contributes to the earliest stages of colorectal cancer by measuring: 1) circulating bile acids; 2) lesional expression of receptors for bile acids and their regulatory networks; and 3) lesional abundance of gut bacteria involved in bile acid metabolism.

For more information about Dr. Passarelli’s seminar or other upcoming seminars please visit the Epidemiology website.

This seminar is hosted at Dartmouth-Health Medical Center in Lebanon, NH, and on Zoom. Registration is required. Register here.

In-person space is limited, so to reserve a seat, you must register AND email Lura.Pascale@dartmouth.edu to confirm space availability.

If you need anything further, please email Epidemiology@dartmouth.edu with your specific request.

Location
Dartmouth-Health Campus and Zoom
Sponsored by
Department of Epidemiology
Audience
Public
Registration required
More information
Lura Pascale