“A Radical Solution for C(sp3)–C(sp3) Bond Formation during the Biosynthesis of Macrocyclic Membrane Lipids”
Bio: Squire J. Booker is an Evan Pugh Professor of Chemistry and of Biochemistry and Molecular Biology
at The Pennsylvania State University and holds the Eberly Family Distinguished Chair in Science. He
is also an Investigator of the Howard Hughes Medical Institute. Booker received a BA degree with a
concentration in Chemistry from Austin College (Sherman, Texas) in 1987. He earned his Ph.D.
degree from the Massachusetts Institute of Technology under Professor JoAnne Stubbe (1994) and
was supported by NSF–NATO and NIH Fellowships for postdoctoral studies in the laboratories of Dr.
Daniel Mansuy (Université René Descartes, Paris, France) and Professor Perry Frey (Institute for
Enzyme Research, University of Wisconsin–Madison), respectively. In 1999 he moved to The
Pennsylvania State University as an independent investigator. Booker’s research concerns novel
mechanisms and pathways for the biosynthesis of various natural products and cellular metabolites,
focusing on enzymes that use S‐adenosylmethionine and iron‐sulfur clusters to catalyze reactions
via radical mechanisms. Currently, he is an Associate Editor for the ACS journal Biochemistry and
Deputy Editor for ACS Bio & Med Chem Gold.