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“When you first get called back, you go through all these ideas of what that might mean,” Anna Tosteson, a professor of medicine at the Geisel School of Medicine, told NPR for a story on mammograms.

Many women are called back for a second mammogram—not necessarily because they actually have cancer but for any number of possible irregularities that appear in the scan. And those follow-ups can cause a great deal of anxiety, even thought most women who are called back will not be diagnosed with breast cancer.

Although the initial follow-up can cause anxiety, Tosteson says, the effect does fade after time. “You think, ‘I’m so glad I don’t have cancer,’” she says.